This cell biology lecture handout, intended for first-year undergraduates at Djilali Bounaama University Khemis Miliana, comprehensively introduces cell structure and function. It covers organism classification, cell theory, prokaryotes, eukaryotes, viruses, and the architecture/roles of key cell components, including the plasma membrane, cytoskeleton, and organelles (nucleus, ribosomes, endoplasmic reticulum, Golgi apparatus). Protein synthesis and genetic information flow are also explored, with emphasis on molecular composition, cellular specialization, cell adhesion, and the extracellular matrix, linking cellular organization to tissue structure and function. The lecture integrates historical context, research methods, and core biological principles to establish a foundation for advanced biological studies.